Population Aging Intensifies, The Phenomenon Of Senile Dementia Will Be Common, How To Prevent It?

According to the United Nations recently released World Population Prospects 2022 report, the global population has reached 8 billion today, and this number will continue to grow in the coming decades, but the growth rate is expected to slow. The global population is expected to rise to about 8.5 billion by 2030, 9.7 billion by 2050, peak at about 10.4 billion in the 2080s, and continue until 2100, the report said. In addition, rising life expectancy, combined with falling fertility rates, will exacerbate global population aging.

What will be the impact on more and more old people? As far as the current situation is concerned, the low fertility rate means that some elderly people will face pension problems in the future. Although these people can apply for relevant policies of the state and enjoy some welfare benefits, they still cannot live peacefully in their old age due to poor physical condition.

In particular, senile dementia, gradually losing memory and becoming a burden to others, is a thing that most elderly people can not accept. Common senile dementias include Alzheimer's disease and vascular dementia.

What symptom does senile dementia have? ‍

1. Early performance

In the early stages of Alzheimer's disease, patients may have intermittent memory loss, such as the way they usually walk, suddenly getting lost one day, or the things they were supposed to do, have not finished several times, and some patients will have the phenomenon of memory dislocation, confusing one thing with another.

2. Medium-term performance

Alzheimer's disease in the middle stage, forget the performance things will be more serious, just happened often can not remember, even forget the name of family, and friends, and can not distinguish between men and women. When the elderly enter this stage of illness, they can no longer take care of themselves and often need family members or special caregivers to take care of them.

3. Late performance

In the middle and late stages of Alzheimer's disease, the elderly will enter completely unable to take care of themselves, even their language function and the ability to move will gradually lose, all aspects of the ability to degrade seriously, resulting in the elderly can only be bedridden.

What should you do in your life to avoid Alzheimer's disease? ‍

1. Nutritional supplements are in place

In order to keep healthy and maintain brain function, it is also important to pay attention to nutrition intake and collocation. The elderly pay attention to a lot of nutrition intake, such as eating more high-protein, high-fiber food, appropriate to reduce the intake of fat, heat, and salt, at the same time should pay attention to avoid inhaling some harmful substances, such as cigarette smoke or alcohol, so as to keep the body environment clear enough, all aspects of function can also operate normally, including the brain. If the elderly diet habits are not good, then the burden of all aspects of the body will be increased, the brain supply of blood and oxygen is insufficient, and the relevant ability will naturally become poor. Among them, there are many foods that protect against Alzheimer's disease, such as milk, eggs, meat and other high-quality protein foods, and Cistanche.

Pic: Faw Cistanche

The survey shows that total glycosides of Cistanche can increase the learning and memory level of AD mice caused by quinolinic acid (QA), reduce the content of malondialdehyde (MDA) in brain tissue caused by quinolinic acid, and increase glutathione peroxidase (glutathione). peroxidase (GSH-Px), superoxide dismutase (superoxide dismutase, SOD) activity, reduce acetylcholine esterase (acetylcholine esterase, TChE) activity, brain cell apoptosis rate, and reduce calcium accumulation in brain tissue. The mechanism may be related to the enhancement of free radical scavenging enzyme activity, reduction of lipid peroxidation, reduction of calcium content in brain tissue, and inhibition of QA-induced brain cell apoptosis; secondly, the total glycosides of cistanche can increase β-AP and aluminum trichloride The result is AD mice's learning and memory level, lower brain tissue MDA content, increase SOD and GSH-Px activity, improve certain pathological changes in brain tissue, and reduce brain cell apoptosis rate. Its mechanism of action is also related to its antioxidant activity.

Pic: Cistanche Benefits

The total glycosides of Cistanche can also have a good protective effect on the ultrastructure of the hippocampus of the D-galactose model mice, and there is a dose-effect relationship. It is speculated that the total glycosides of cistanche may delay aging and prevent Alzheimer's disease through an antioxidant mechanism. effect.

Pic: Effects of Cistanche treat Alzheimer‘s disease

Cistanche extract can increase the protein expression levels of nicotinic acetylcholine receptor (nAChR) α3 and α7 receptor subunits in SH-SY5Y cells, and resist the levels of α3 and α7 receptor subunits caused by Aβ25-35 The reduction of Aβ can reduce the cell damage and the increase of lipid peroxidation level caused by Aβ; it can also promote the axon growth of rat pheochromocytoma (PC12) cells and increase rat glioma (Giiomas, C6) cells The level of nerve growth factor (NGF), as well as mouse hippocampal axon growth, neuron differentiation, and synapse formation, and can stimulate the secretion of NGF in mouse cortex and hippocampus, significantly improving the learning and memory ability of mice. These effects show that the traditional Chinese medicine Cistanche deserticola extract has the potential to be a drug for the treatment of AD.

Click here to find out more about Cistanche

2. Socialize

In fact, not only young people, but the elderly also need social, nothing and peers together playing mahjong, chess, dancing square is very good, not only can make friends but also can exercise the body, enhance the brain, very healthy.

With peers, it is easier for the elderly to find common topics and hobbies. If what they like is adhered to, the elderly's brain will be constantly exercised to avoid the situation of mental decline.

3. Increase activities that stimulate your brain

People's brains are more flexible, even into old age, and will follow this law, if the elderly lack mental exercise in life, then the relevant ability of the brain will show a trend of decline, and the probability of dementia will increase in the future.

Therefore, it is suggested that the elderly should have more mental exercise in their life, such as forming the habit of exercise, playing some puzzles, or getting along with the young people around them and getting in touch with some fresh "knowledge points". Only when the brain is constantly developed, can the abilities of all aspects of the brain be maintained at a normal level?

4. Adjust your attitude

Some elderly people will be overly nervous about Alzheimer's disease. For example, one day, they suddenly forget one thing and feel that they have dementia. Such a mentality is not advisable. Long-term self-suggestion will affect the mental state of the elderly, the mentality is not correct will affect the mood, the greater the mood fluctuation, the more negative stimulation of the brain, but not conducive to health. It is suggested that we put a flat attitude in life, and always keep optimistic, so that it is more conducive to health.

Therefore, Alzheimer's disease can be prevented, as long as the above points, can properly reduce the risk of suffering from this disease.